Nilandron (nilutamide) for advanced prostate cancer
Hoechst is introducing Nilandron (nilutamide) for advanced prostate cancer.
Nilandron is an antiandrogen...similar to Eulexin (flutamide) and Casodex (bicalutamide). These drugs help reduce metastatic bone pain and improve survival.
Both Nilandron and Casodex are dosed once a day...instead of TID like Eulexin. But Nilandron isn't as well-tolerated as Casodex. It frequently causes visual disturbances...mainly a delay in adjusting from light to dark. Warn patients about driving at night.