Drug interactions are now a hot research topic
Drug interactions are now a hot research topic...especially those associated with cytochrome P450 enzymes in the liver. Two important interactions have just been reported...and aren't in most pharmacy computer systems yet.
The oral antifungal, itraconazole (Sporanox), DRAMATICALLY increases levels of lovastatin (Mevacor)...about a twentyfold increase.
A similar interaction might also occur with simvastatin (Zocor)...and possibly the other statins.