Prozac (fluoxetine) or Zoloft (sertraline) INTERMITTENTLY instead of daily for PMS

June 1998

Some physicians now prescribe Prozac (fluoxetine) or Zoloft(sertraline) INTERMITTENTLY instead of daily for PMS.

These SSRIs are being used for a specific type of PMS calledpremenstrual dysphoric disorder (PMDD). Women with PMDD have moremood changes...anxiety...or irritability.

SSRIs are often effective for PMDD. But women usually takethese drugs all month long...even though they only have symptomsduring part of their cycle.

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