Watch for Direct Oral Anticoagulant (Pradaxa, etc) Drug Interactions

May 2016

You'll see drug interaction alerts pop up with direct oral anticoagulants (DOACs) such as Pradaxa (dabigatran).

We know interactions are less common with DOACs than warfarin.

But Eliquis (apixaban) and Xarelto (rivaroxaban) are metabolized by CYP3A4...and absorption of all 4 DOACs is affected by P-glycoprotein.

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