Don't Routinely Check B12 Levels in Most Patients Taking Metformin

May 2016

You'll get questions about metformin and vitamin B12 deficiency.

Up to 1 in 14 patients taking metformin for about 4 years develop B12 deficiency. It's probably even more common with longer use.

Consider whether metformin may be contributing if you happen to find macrocytic anemia on a routine CBC...or in patients with neuropathy.

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