kidney problems when clarithromycin is combined with a calcium channel blocker (amlodipine, etc)

January 2014

You'll get alerts about kidney problems when clarithromycin is combined with a calcium channel blocker (amlodipine, etc).

Clarithromycin is a strong 3A4 inhibitor that can slow the metabolism of calcium channel blockers and increase their levels.

This can lead to hypotension...edema...bradycardia...and acute kidney injury due to reduced perfusion.

Get concise, unbiased advice for effective drug therapy, plus CE/CME

Prescriber Insights: APRN includes:

Cutting-edge advice about new medications and how they fit into practice
Unbiased, evidence-based, 100% free of financial support from the pharma industry written by your peers
Side-by-side comparisons of drugs by class or disease state, plus FAQs, pros/cons, and simple recommendations

Already a subscriber? Log in

Volume pricing available. Get a quote