Think Twice Before Prescribing TMP/SMX With Potassium-Boosting Meds

January 2015

You'll hear more about possible harm when TMP/SMX (Bactrim, etc) is combined with meds that increase potassium (ACEIs, spironolactone, etc).

This interaction is more risky than previously thought...and is popping up on more drug interaction software.

Trimethoprim decreases urinary excretion of potassium.

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Table of Contents

Chronic Illness Document Non-Face-to-Face Care to Get Additional Medicare Payments
Dyslipidemia Save Ezetimibe as an Add-On in High-Risk Patients
Hypothyroidism Explain That Full Benefit of Levothyroxine May Take 6 Months
Antithrombotics Don't Use Newer Oral Anticoagulants for VTEs During Pregnancy
Pediatrics Use Supportive Care Instead of Meds for Bronchiolitis in Kids
Diabetes Use the Shortest and Thinnest Insulin Needle Available
Bipolar Disorder Lean Away From Aripiprazole or Ziprasidone for Bipolar Depression
COPD Choose Between Spiriva Handihaler and Respimat Based on Patient Preference
Eye Health Help Dry-Eye Patients Avoid Topical Vasoconstrictors
Med Administration Recommend a Different Head Position to Make Swallowing Pills Easier
Interactions Think Twice Before Prescribing TMP/SMX With Potassium-Boosting Meds
Generics Write for "Methylphenidate Extended-Release" Instead of Concerta