Move to the CKD-EPIcr Creatinine Equation for Kidney Dosing

October 2026

New guidance stresses switching to the 2021 CKD-EPI creatinine (CKD-EPIcr) equation to estimate kidney function for drug dosing in adults.

Before, pharmacists and EHRs generally used the Cockcroft-Gault equation from the 1970s to estimate creatinine clearance for med dosing.

Now, the National Kidney Foundation and other organizations advocate transitioning to the CKD-EPIcr equation...it’s considered more accurate.

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