Navigate the Discontinuation of Humulin R U-500 Vials

March 2026

Humulin R U‑500 insulin VIALS are being discontinued...and you’ll need to help patients switch to an alternative.

For years, this concentrated regular insulin has come in a 20 mL vial or a KwikPen...with 500 units/mL instead of the usual 100 units/mL.

Now the U-500 vials are going away...likely due to business reasons. Plus, using U-500 vials is commonly associated with serious errors.

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