Clarify Midline IV Catheter Use, Safety, and Best Practices

March 2026

Questions are starting to come up about whether to treat midline IV catheters as peripheral or central lines...or somewhere in between.

Midlines are being used more in emergency departments and outpatient antibiotic therapy due to better convenience and cost compared to PICCs.

Clarify that midlines are still considered peripheral IV (PIV) lines. They’re usually inserted into the crook of the elbow. But the line tip ends near the armpit...not the vena cava like for central lines.

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