Don’t Jump to Ubrelvy or Reyvow for Acute Migraine Treatment
You’ll see new oral meds to treat acute migraine in adults, Ubrelvy (yoo-BREL-vee, ubrogepant) and Reyvow (RAY-vow, lasmiditan).
Ubrelvy is the first “gepant”...expect rimegepant to follow. They block receptors of calcitonin gene-related peptide (CGRP), a vasodilator and pain sensitizer that spikes during migraine attacks.
They’re different than the injectables for PREVENTION (Aimovig, Ajovy, Emgality)...monoclonal antibodies that block CGRP effects.