Don't Jump to Combo Med Duzallo for Chronic Gout
Duzallo (doo-ZAL-oh) will be a new chronic gout med that combines lesinurad with allopurinol.
Reps will tout Duzallo as a combo that targets both causes of gout. Allopurinol decreases uric acid production...and lesinurad (Zurampic) increases renal uric acid excretion, similar to probenecid.
Duzallo helps about one more in 4 patients reach uric acid goals...compared to about 300 mg/day of allopurinol alone.