Use eGFR Instead of Cockcroft Gault for "Flozin" Dosing

February 2015

You'll get questions about using estimated glomerular filtration (eGFR) for renal dosing of meds.

We're used to seeing renal adjustments based on creatinine clearance (CrCl). This is still the case for over 95% of drugs.

But now eGFR is showing up in labeling for some drugs...such as the "flozins" (Invokana, etc).

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Table of Contents

Vaccines Explain Antivirals Don't Help the Flu in Most Patients
Obesity & Weight Loss Reduce Insulin Doses if Saxenda is Used for Weight Loss in Diabetes
Opioids Watch for Hypoglycemia Right After Starting Tramadol
Cough & Cold Resist Temptation to Recommend OTC Dextromethorphan or Guaifenesin for Cough
Med Administration Consider Using Some Eye Drops Sublingually
Neurology & Pain Recommend Increasing Power Gradually on OTC "TENS" Devices
Insomnia Caution Patients Belsomra Can Cause "Sleep Driving"
Menopause Avoid Soy Supplements in Women With Breast Cancer
Sickle Cell Disease Try a Progestin-Only Contraceptive for Sickle Cell Patients
Blood Pressure Tell Patients to Check Blood Pressure BEFORE Taking Their Meds
Hepatitis C Be Aware Viekira Still Needs to Be Used With Ribavirin
ADHD Add Atomoxetine for ADHD When Methylphenidate Isn't Enough
Practice Manage Postoperative Pain to Reduce Delirium Risk
Renal & Urology Use eGFR Instead of Cockcroft Gault for "Flozin" Dosing
Hemophilia Don't Use Obizur for Congenital Hemophilia A