proton pump inhibitors (PPIs) might DECREASE the efficacy of clopidogrel (Plavix)

April 2009

There's growing concern that proton pump inhibitors (PPIs) might DECREASE the efficacy of clopidogrel (Plavix).

At first many experts dismissed this because it was based on in vitro platelet aggregation studies...not clinical outcomes.

Now some new published and unpublished studies suggest that patients taking clopidogrel plus a PPI actually have more cardiovascular events.

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Table of Contents

proton pump inhibitors (PPIs) might DECREASE the efficacy of clopidogrel (Plavix)
Antithrombotics when and how to use vitamin K to reverse the effects of warfarin
Cardiology whether it's HARMFUL to combine an ACE inhibitor and ARB
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