Metoclopramide will have a new black box warning about the risk for tardive dyskinesia

April 2009

Metoclopramide will have a new black box warning about the risk for tardive dyskinesia.

We usually associate this movement disorder with haloperidol and other traditional antipsychotics.

But it's also seen with metoclopramide (Reglan, etc)... especially with chronic use or high doses.

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Table of Contents

proton pump inhibitors (PPIs) might DECREASE the efficacy of clopidogrel (Plavix)
Antithrombotics when and how to use vitamin K to reverse the effects of warfarin
Cardiology whether it's HARMFUL to combine an ACE inhibitor and ARB
Psychiatry how to treat dementia associated with Parkinson's
Psychiatry metabolic acidosis in patients taking the antiepileptic, zonisamide (Zonegran, etc)
Respiratory & Allergy Symbicort (budesonide/formoterol) will be used more for COPD
Respiratory & Allergy patients on Afrin or other nasal decongestants get rebound congestion
Gastroenterology Metoclopramide will have a new black box warning about the risk for tardive dyskinesia
Pediatrics Miralax is being used more to treat constipation in kids
Diabetes controversy about using glyburide for type 2 diabetes
Shortages alternatives to oxycodone
Infectious Diseases LESS cross-sensitivity between penicillins and carbapenems than most clinicians think
Gout Uloric (YOU-lor-ik, febuxostat) is the first new chronic treatment for gout in over 40 years