both a proton pump inhibitor PLUS an H2-blocker for GERD

March 2007

More patients are getting both a proton pump inhibitor PLUS an H2-blocker for GERD.

PPIs don't provide continuous acid suppression...even with BID dosing. Nighttime acid breakthrough occurs in over 70% of patients.

Keep in mind that PPIs only inhibit ACTIVE proton pumps, so they work best when acid secretion is being triggered by a meal.

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