serotonin syndrome in patients taking fluoxetine (Prozac, etc) with the HIV drug ritonavir (Norvir, Kaletra).

September 2001

There are reports of serotonin syndrome in patients taking fluoxetine (Prozac, etc) with the HIV drug ritonavir (Norvir, Kaletra).

Ritonavir is a potent inhibitor of cytochrome P450 enzymes... and can slow the metabolism of fluoxetine.

The combination can lead to symptoms of serotonin syndrome... confusion, muscle spasms, tremor, fever, anxiety, etc.

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Table of Contents

the safety of Celebrex and Vioxx.
Diabetes trying to PREVENT type 2 diabetes.
Obesity & Weight Loss psyllium (Metamucil, etc) can reduce some of the unpleasant GI effects of Xenical (orlistat).
Cardiology Now that Baycol (cerivastatin) is off the market, patients are asking whether the other statins are safer.
Cardiology new IV drug for acute heart failure called Natrecor (nesiritide).
Several theophylline products are going off the market.
oral dexamethasone instead of prednisone for acute pediatric asthma.
serotonin syndrome in patients taking fluoxetine (Prozac, etc) with the HIV drug ritonavir (Norvir, Kaletra).
Zyprexa (olanzapine) for anorexia nervosa
Infectious Diseases how to treat a healthcare worker exposed to hepatitis or HIV from needle sticks, etc
Infectious Diseases whether condoms prevent sexually transmitted diseases
Women's Health chronic hypertension during pregnancy
Hematology & Oncology huge study to determine whether vit E or selenium prevent prostate cancer
Hematology & Oncology new IV bisphosphonate called Zometa (zoledronic acid)
Malaria most travelers shouldn't rely on chloroquine to prevent malaria