High-dose ranitidine (Zantac) usually ISN'T more effective

April 1999

High-dose ranitidine (Zantac) usually ISN'T more effective than standard doses for gastroesophageal reflux disease (GERD).

Managed care organizations often recommend starting with ranitidine 150 mg BID for 6 to 8 weeks...then increasing the dose to 300 mg BID if symptoms persist.

But increasing the dose usually doesn't help. Fewer than half of patients have complete relief on either dose of ranitidine.

Get concise, unbiased advice for effective drug therapy, plus CE/CME

Prescriber Insights: APRN includes:

  • Cutting-edge advice about new medications and how they fit into practice
  • Unbiased, evidence-based, 100% free of financial support from the pharma industry written by your peers
  • Side-by-side comparisons of drugs by class or disease state, plus FAQs, pros/cons, and simple recommendations

Already a subscriber? Log in

Volume pricing available. Get a quote