significant interaction when verapamil is combined with lovastatin (Mevacor) or simvastatin (Zocor)

November 1998

Researchers are reporting a significant interaction when verapamil is combined with lovastatin (Mevacor) or simvastatin (Zocor).

Verapamil seems to slow the metabolism of lovastatin and simvastatin...allowing their levels to build up.

A similar interaction can also occur when these two statins are combined with erythromycin...clarithromycin...ketoconazole...itraconazole...nefazodone...cyclosporine...or grapefruit juice.

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