HIV patients taking a combination of two protease inhibitors

December 1997

    You'll see more HIV patients taking a combination of two protease inhibitors...instead of the usual triple therapy.

    The most common protease inhibitor combo is ritonavir (Norvir) plus saquinavir. This combo makes sense. Ritonavir inhibits the metabolism of saquinavir...increasing saquinavir levels 17-fold.

    This results in better viral suppression...comparable to the usual triple drug regimens.

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