Rabies Post-Exposure Prophylaxis: Bat to the Basics

November 2026

Questions about rabies post-exposure prophylaxis (PEP) are starting to bite...due to a recent CDC alert about rising human rabies exposures.

Rabies is almost always fatal...but PEP prevents it when given promptly and correctly after an exposure, before symptoms start.

Refer patients with a possible exposure to the ED right away...unless you can start PEP in office. If so, contact your health department for a risk assessment to help decide whether it’s needed.

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