Clarify the Role of “Gepants” for Managing Migraine
February 2024
You can help sort through the growing list of “gepants” for managing migraine...Nurtec ODT, Qulipta, Ubrelvy, and Zavzpret.
Gepants block receptors of calcitonin gene-related peptide (CGRP), a vasodilator and pain sensitizer that spikes during a migraine.
They’re different than the injectable CGRP antagonists...erenumab (Aimovig), fremanezumab (Ajovy), and galcanezumab (Emgality). These are monoclonal antibodies for prevention.
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