Know Who Should Get Penicillin for Sickle Cell Disease
December 2024
Penicillin prophylaxis for pediatric sickle cell disease (SCD) needs your attention...since adherence is low and some kids no longer need it.
About 100,000 US patients have SCD. The sickled red blood cells can lead to splenic infarction, impairing its immune functions...and increasing risk for invasive pneumococcal disease.
Penicillin prophylaxis for 15 months prevents pneumococcal infections in 1 in 10 patients with SCD...and may improve survival.
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