Tailor DAPT Duration for Patients at High Bleeding Risk

June 2023

You’ll hear debate about shorter dual antiplatelet therapy (DAPT) durations after a stent in acute coronary syndrome (ACS).

The standard has been DAPT with aspirin AND a P2Y12 inhibitor (clopidogrel, prasugrel, or ticagrelor) for 12 months...with the option to extend for those at high thrombotic and low bleeding risk.

But mounting evidence suggests that 1 to 3 months of DAPT may be enough for select patients with ACS...such as those with high bleeding risk due to advanced age, prior GI or intracranial bleeding.

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