Stay Alert for Opioid-Induced Hyperalgesia

July 2023

You’ll get questions about opioid-induced hyperalgesia...due to a recent FDA warning and opioid label changes.

Opioids can sometimes paradoxically cause increased pain, hyperalgesia...or pain from nonpainful stimuli, allodynia.

Opioid-induced hyperalgesia can happen with a range of opioids. Explain that it’s more likely with higher doses and longer durations, but onset varies...and the exact incidence isn’t known.

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