Save Brexafemme and Solosec as a Last Resort for Vaginal Infections

September 2021

New meds and indications will lead to questions about how to treat vaginal infections.

Brexafemme (ibrexafungerp) will be touted as an oral, one-day med that is fungicidal against Candida...versus azoles, which are fungistatic.

But it doesn’t seem to work better than vaginal azoles (clotrimazole, etc) or oral fluconazole...the first-line meds for uncomplicated candidiasis. These are effective in 80% to 90% of cases.

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