Plan Your Strategy to Reverse Warfarin or DOAC Bleeds

September 2020

You’ll need to determine the best way to reverse major bleeding caused by oral anticoagulants...as experts continue to debate.

First, stop the anticoagulant...and use supportive bleeding control measures. Add a reversal agent for life-threatening or critical site bleeds (intracranial, retroperitoneal, etc).

Warfarin. Generally use 4-factor prothrombin complex concentrate (Kcentra)...plus IV vitamin K.

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Plan Your Strategy to Reverse Warfarin or DOAC Bleeds

Get concise, unbiased advice for effective drug therapy, plus CE/CME

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