Consider Using Subcutaneous Methotrexate More for Rheumatoid Arthritis

April 2018

You'll see more methotrexate options for rheumatoid arthritis.

Oral methotrexate is still first-line for rheumatoid arthritis. But some patients may find it hard to tolerate...making it tempting to go to other DMARDs (sulfasalazine, etc) or biologics (Humira, etc) too soon.

Evidence suggests SUBCUTANEOUS methotrexate may have fewer GI side effects than oral and be more effective because it's better absorbed...especially at doses of 15 mg or more per week.

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