Don't Add Tolvaptan (Samsca) to Improve Diuresis in HF Patients

December 2016

New evidence will bring up questions about the best way to diurese acute decompensated heart failure (ADHF) patients.

We know to give volume-overloaded patients IV loop diuretics (furosemide, etc). But side effects, such as renal dysfunction and electrolyte abnormalities, have created a push to find better options.

Hopes were set on tolvaptan (Samsca). It's used to treat severe hyponatremia by blocking vasopressin and increasing free water excretion.

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