Explain How Exparel Compares to Other Local Anesthetics for Post-Op Pain

November 2014

Questions are coming up about the best treatments for postoperative pain...due to new products and the push to reduce adverse opioid effects.

Consider acetaminophen or NSAIDs first-line for mild to moderate pain. Or add these for opioid-sparing effects for more severe pain.

There's no proof IV acetaminophen (Ofirmev) is better than oral or rectal forms...and the IV costs $35 per 1000 mg dose. Save IV acetaminophen for when oral or rectal can't be used...and consider restricting its use to the perioperative period.

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