the interaction between simvastatin (Zocor, etc) and amlodipine (Norvasc, etc)

September 2011

New alerts will raise new questions about the interaction between simvastatin (Zocor, etc) and amlodipine (Norvasc, etc).

Some prescribers are surprised...because amlodipine is only a weak inhibitor of simvastatin metabolism by CYP3A4 enzymes.

But the combo IS associated with a higher risk of myopathy.

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Table of Contents

Cardiology the risk of stopping aspirin, clopidogrel, or other antiplatelet drugs too soon
Statins the interaction between simvastatin (Zocor, etc) and amlodipine (Norvasc, etc)
Lice Natroba (nah-TRO-buh), a new Rx topical suspension for head lice
Psychiatry stronger warnings about Seroquel and QT prolongation
Geriatrics "START" and "STOPP" instead of Beers to evaluate appropriate med use in the elderly
Infectious Diseases new strain of ceftriaxone-resistant gonorrhea
Acetaminophen changes to OTC Tylenol and other acetaminophen products
Anticoagulants how to reverse bleeding due to Pradaxa or Xarelto
Migraine whether it's okay to use triptans (sumatriptan, etc) for migraines in CHILDREN
Parkinson's Disease treating Parkinson's disease AFTER the "honeymoon" is over
Diabetes Patients are asking about a new "bloodless" glucose meter
Edema how to handle peripheral edema due to dihydropyridine calcium channel blockers (amlodipine, etc)