serious allergic reactions to the antipsychotic, Saphris (asenapine)

October 2011

You'll see new warnings about serious allergic reactions to the antipsychotic, Saphris (asenapine).

There are 52 reports of anaphylaxis, angioedema, and other Type 1 hypersensitivity reactions in its first year on the market.

And some of these reactions occur after just the FIRST dose...instead of requiring sensitization first.

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Table of Contents

Anticoagulants controversy over which ORAL anticoagulant to use to prevent strokes in patients with atrial fibrillation
Antidepressants citalopram doses should not exceed 40 mg/day for anyone...or 20 mg/day for most patients over age 60
Antidepressants Reps are filling up sample closets, hoping prescribers will use Deplin to improve the efficacy of antidepressants
Respiratory & Allergy chronic azithromycin to PREVENT recurrent COPD exacerbations
Influenza the first INTRADERMAL flu vaccine
Women's Health tighter and more aggressive control of hypothyroidism before and during pregnancy
Opioids two new opioid formulations, Oxecta and Lazanda
Antipsychotics serious allergic reactions to the antipsychotic, Saphris (asenapine)
Cardiology MORE safety concerns with dronedarone (Multaq)
Geriatrics manage elderly dementia patients who have behavior issues
Interactions Computers often give an "interaction alert" when potassium chloride tabs or caps are combined with an anticholinergic drug
Corticosteroids We're getting questions about whether hyperglycemia can occur with non-oral corticosteroids