appropriate antibiotics for empiric treatment of complicated intra-abdominal infections

New guidelines will clarify appropriate antibiotics for empiric treatment of complicated intra-abdominal infections.

Community-acquired infections. For appendicitis and other mild to moderate community infections use a single agent such as cefoxitin or ticarcillin/clavulanate (Timentin)...or combo therapy such as metronidazole plus cefazolin or ceftriaxone.

Reserve tigecycline (Tygacil) because of its broader spectrum... and ertapenem (Invanz) to reduce the risk of carbapenem resistance.

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