proton pump inhibitors (PPIs) might decrease the antiplatelet effects of clopidogrel (Plavix)
November 2008
For updated information on this topic, please see Detail-Document #250401
Aetna is sending out an alert that proton pump inhibitors (PPIs) might decrease the antiplatelet effects of clopidogrel (Plavix).
They suggest not using a PPI with clopidogrel unless there is a high risk of GI bleeding.
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