long-acting opioids more frequently than the preferred dosing schedule recommended by the manufacturer

Some patients may need long-acting opioids more frequently than the preferred dosing schedule recommended by the manufacturer.

Some patients use fentanyl patches every 24 to 48 hours...instead of every 72 hours. Many OxyContin and MS Contin users wind up taking them TID to QID...rather than BID.

Try increasing the DOSE before decreasing the dosing INTERVAL for patients who are not getting adequate pain relief.

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