genetically test many Asians BEFORE starting carbamazepine

February 2008

You should now genetically test many Asians BEFORE starting carbamazepine...to predict their risk of a serious drug reaction.

This is big. It's the first time that genetic screening is recommended for a mainstream drug.

Carbamazepine (Tegretol, etc) now has a black box warning on this. It recommends that patients of Asian descent be screened for the HLA-B*1502 gene before starting therapy.

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