Bone loss due to long-term Depo-Provera may not be as much of a problem as the black box warning suggests

December 2008

Bone loss due to long-term Depo-Provera may not be as much of a problem as the black box warning suggests.

The warning says not to use Depo-Provera (medroxyprogesterone) over 2 years...except as a last resort.

But many women use it longer for convenient effective birth control.

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