Some prescribers still shy away from using thiazides first-line for hypertension due to concerns about inducing diabetes

January 2007

Some prescribers still shy away from using thiazides first-line for hypertension due to concerns about inducing diabetes.

It's true that thiazides increase the risk of hyperglycemia and new-onset diabetes.

But a new analysis of the large ALLHAT hypertension trial shows that this does NOT translate into a higher risk of CV events or death.

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