misconceptions about grapefruit juice interactions

February 2007

There are still misconceptions about grapefruit juice interactions.

We've known for years that grapefruit inhibits CYP3A4 and P-glycoprotein in the gut...and that this increases levels of some calcium channel blockers (felodipine, etc), statins (lovastatin, simvastatin), anti-arrhythmics (amiodarone), and others.

But misunderstandings still cloud the best way to handle this.

Get concise, unbiased advice for effective drug therapy, plus CE/CME

Prescriber Insights: APRN includes:

Cutting-edge advice about new medications and how they fit into practice
Unbiased, evidence-based, 100% free of financial support from the pharma industry written by your peers
Side-by-side comparisons of drugs by class or disease state, plus FAQs, pros/cons, and simple recommendations

Subscribe Today!

Already a subscriber? Log in

Volume pricing available. Get a quote

You'll see manufacturers market more metabolites and isomers of existing drugs to replace drugs with expiring patents
Osteoporosis whether proton pump inhibitors (omeprazole, etc) increase the risk for fractures
Osteoporosis Women are hearing that they can take a break from their oral bisphosphonate (Fosamax, etc)
Interactions misconceptions about grapefruit juice interactions
Men's Health anticholinergics (Detrol, Ditropan, etc) for urinary symptoms in men with benign prostatic hyperplasia
Cardiology Patients are asking if their meds for Parkinson's or restless legs will cause heart trouble
Cardiology Plavix and aspirin combo for at least 12 months after getting a drug-eluting coronary stent
Substance Use Disorder dextromethorphan abuse in teens
Vaccines You'll be giving more human papillomavirus, pertussis, and herpes zoster vaccines
Dermatology New evidence is helping to clear up what works for rosacea
Hormone Therapy controversy about bioidentical hormones
Infectious Diseases Ketek will eventually be severely curtailed or go off the market
Practice the significant new drugs approved in 2006

misconceptions about grapefruit juice interactions

Get concise, unbiased advice for effective drug therapy, plus CE/CME

Table of Contents