statins decrease the effects of Plavix

You might hear that statins decrease the effects of Plavix.

Plavix (clopidogrel) is converted to its ACTIVE form through cytochrome P450 3A4 metabolism.

Since Lipitor, Zocor, and lovastatin are all metabolized by cytochrome P450 3A4, researchers theorize that Plavix and these statins might compete...and therefore reduce the effects of Plavix.

Get concise, unbiased advice for effective drug therapy, plus CE/CME

Prescriber's Letter includes:

  • 12 issues every year, with brief articles about new meds and guidelines
  • 48+ CE courses, including the popular CE-in-the-Letter
  • Quick reference drug comparison charts
  • Access to the entire archive

Already a subscriber? Log in

Volume pricing available. Get a quote