Is trimethoprim-sulfamethoxazole effective for resistant UTI

Is trimethoprim-sulfamethoxazole effective for resistant UTI?

TMP-SMZ is preferred for uncomplicated UTI. But some regions are now developing high resistance rates to this antibiotic.

Many clinicians still try TMP-SMZ for patients with resistant UTI. The thinking is that TMP-SMZ reaches such high concentrations in the urine that it can overcome resistance.

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