reduce the dose of Pepcid even in patients with MODERATE renal impairment

May 2001

There's now a new warning to reduce the dose of Pepcid even in patients with MODERATE renal impairment.

Pepcid is excreted renally. A lower dose is already recommended for SEVERE renal insufficiency...creatinine clearance < 10 mL/min.

Now Merck also recommends lowering the dose for patients with MODERATE renal insufficiency...creatinine clearance < 50 mL/min.

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Table of Contents

new guidelines for treating acute exacerbations of COPD
Diabetes Lantus, the new long-acting "peakless" insulin
Alzheimer's Disease Reminyl (galantamine) for Alzheimer's
Gastroenterology reduce the dose of Pepcid even in patients with MODERATE renal impairment
Cholesterol severe myopathy in patients taking both a statin and gemfibrozil (Lopid)
Pediatrics TMP/SMX (Septra, etc) for head lice
Pediatrics rickets is making a comeback
Paxil is now approved for generalized anxiety disorder
latest news reports that say St. John's wort isn't effective for depression
Ophthalmology two new eyedrops for glaucoma
Ophthalmology patients getting severe migraines after using Xalatan (latanoprost) eyedrops
Ophthalmology Valcyte (valganciclovir) tablets, an improved version of oral Cytovene (ganciclovir)
Dermatology Aldara (imiquimod cream) to reduce the recurrence of keloid scars
Asthma treat acute asthma exacerbations with high doses of INHALED steroids
Hematology & Oncology mistletoe for breast cancer
Hematology & Oncology melatonin might help prevent or treat breast cancer
Shortages Drug shortages are becoming more common