Nexium, a follow-up to their Prilosec proton pump inhibitor

March 2001

AstraZeneca is now launching Nexium, a follow-up to their Prilosec proton pump inhibitor.

Nexium (esomeprazole) is just the S-isomer of Prilosec. Prilosec (omeprazole) is a mixture of S- and R-isomers.

The S-isomer is metabolized slower. This leads to higher and more prolonged drug concentrations and longer acid suppression.

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