whether it makes sense to use BOTH an H2-blocker and a proton pump inhibitor (PPI) for GERD

We're getting questions about whether it makes sense to use BOTH an H2-blocker and a proton pump inhibitor (PPI) for GERD.

It does...sometimes.

PPIs are effective for most GERD patients. But some have breakthrough acid secretion at night...even if they take PPIs twice a day.

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