drug interactions with St. John's wort

March 2000

The list of drug interactions with St. John's wort is growing.

We know this popular herb can interact with digoxin...warfarin...and SSRIs (Prozac, etc).

Now there are reports of an interaction with cyclosporine...resulting in acute heart transplant rejection.

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Table of Contents

many patients are getting drug doses that are too high
Gastroenterology Lotronex (alosetron), a new drug for irritable bowel syndrome (IBS)
Cardiology whether vitamin E reduces the risk of coronary heart disease
Pediatrics Augmentin is more effective than Zithromax for acute otitis media
Pediatrics Prevnar, the first pneumococcal vaccine for children under 2
Ophthalmology three new eye drops for itching due to allergic conjunctivitis
counteract sexual dysfunction caused by SSRIs (Prozac, etc)
SSRIs can cause patients to clench and grind their teeth
Women's Health Ortho-Prefest, a new combo HRT regimen
Women's Health metformin and other insulin-sensitizing drugs for Polycystic Ovary Syndrome (PCOS)
which calcium supplement to recommend for a particular patient
Infectious Diseases Levaquin (levofloxacin) for treating penicillin-resistant pneumococcal pneumonia
Infectious Diseases Sporanox (itraconazole) now comes in IV form
drug interactions with St. John's wort