warning patients not to drink grapefruit juice while taking Propulsid (cisapride)

Janssen is now warning patients not to drink grapefruit juice while taking Propulsid (cisapride).

Grapefruit juice increases the absorption of Propulsid...by inhibiting its metabolism in the GI tract.

The problem is that high levels of Propulsid can lead to life-threatening arrhythmias.

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