new warnings of liver dysfunction in patients taking Precose (acarbose)

September 1998

You'll see new warnings of liver dysfunction in patients taking Precose (acarbose). There are over 60 reports...including two deaths.

We usually don't think of hepatic toxicity with Precose...it works in the GI tract. Very little acarbose is even absorbed...but some of the metabolites are absorbed, and might cause hepatic problems.

Hepatic dysfunction is more common at high doses.

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