restricting the use of Tasmar (tolcapone) due to reports of serious hepatotoxicity

December 1998

The FDA recommends restricting the use of Tasmar (tolcapone) due to reports of serious hepatotoxicity...including three deaths.

Tasmar came out earlier this year. It's used to prolong the effect of levodopa in patients with advanced Parkinson's.

Now the FDA recommends limiting Tasmar to patients who can't take or don't respond to other Parkinson's drugs.

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Table of Contents

new drugs coming out for rheumatoid arthritis
Infectious Diseases new precautions about hepatotoxicity with the new quinolone, Trovan (trovafloxacin)
Infectious Diseases surprising interaction between ORAL Trovan and IV morphine
new question about whether it might cause neurotoxicity
Interactions add carbamazepine (Tegretol) to the list of drugs that can interact with grapefruit juice
Interactions which anticonvulsants interact with hormonal contraceptives
Cardiology updated their guidelines for preventing stroke in patients with atrial fibrillation
Pediatrics Versed (midazolam) now comes as an ORAL syrup
Pediatrics Robi Comb to electronically "zap" head lice
Pediatrics Many parents of autistic kids are asking about secretin
Breast Cancer The National Cancer Institute is now offering "Risk Disk"
Substance Use Disorder people getting addicted to OTC stimulants
Substance Use Disorder first drug abuse test that can be performed AT HOME
Substance Use Disorder reclassify Marinol (dronabinol) from Schedule II to Schedule III
Asthma Pulmicort Turbuhaler (budesonide) is now approved for ONCE daily dosing
Neurology & Pain restricting the use of Tasmar (tolcapone) due to reports of serious hepatotoxicity
possible link between hepatitis B vaccination and autoimmune disorders
backlash from managed care against all the drug ads on TV, radio, magazines, etc