Some patients on Crixivan or other protease inhibitor combo therapy are noticing an unusual side effect

April 1998

Some patients on Crixivan or other protease inhibitor combotherapy are noticing an unusual side effect...an accumulation of fatin the waist, stomach, or the back of the neck.

This syndrome is being called "protease paunch"..."buffalohump"...or "Crix belly."

It looks like Cushing's syndrome...but it DOESN'T seem to becaused by high cortisol levels like Cushing's.

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