Maxipime (MAXI-peem, cefepime), the first "fourth-generation" injectable cephalosporin

June 1996

Bristol-Myers Squibb is launching Maxipime (MAXI-peem, cefepime), the first "fourth-generation" injectable cephalosporin.

In general, the first-generation agents are primarily active against gram-positive bacteria.

Second and third generations have increasing gram-negative coverage...sometimes at the expense of reduced gram-positive activity.

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